Antithrombin III activity

• The test material is blood.
• The patient does not need to be fasting.

Samples brought from outside are not accepted for testing.

Antithrombin (AT), commonly known as antithrombin III, is the most important blood coagulation inhibitor of the serine protease inhibitor group. In the body, it primarily serves as an anticoagulant in the coagulation system.AT is produced in the liver. Clotting factors inactivated by AT include thrombin (IIa), IXa, Xa, XIa, XIIa. AT activity is tested primarily in the course of thromboembolism to detect acquired and congenital deficiencies of AT.
Decreased AT activity is observed in congenital thrombophilia, liver disease ( parenchymal damage and reduced ability to synthesize proteins), nephrotic syndrome
( excessive excretion), exudative enteropathy and severe burns ( loss of proteins), DIC syndrome, physiologically in premature infants and newborns, as well as in chronic treatment with heparin and L-asparaginase.
Elevated AT levels have no diagnostic significance; an increase in AT is observed in inflammation ( acute phase protein)and vitamin K deficiency.

Enter a one-time code:Show
An invalid code has been entered. Please try again.