Study of mutations in exons 4-10 of the TP53 gene

Material: Blood
Test price: PLN 1,656
Waiting time for results: result after 21 working days
Reservation:

  • Advance booking required by calling 81 532 37 11.

Preparation for the examination

General

  • The test is collected at a dedicated Collection Point.
  • The patient does not need to fast. It is recommended to drink a glass of water approximately 30 minutes before the examination.

Important

Samples brought from outside are not accepted for testing.

Description

"Analysis of mutations in exons 4-10 of the TP53 gene.
The tumor suppressor gene TP53 (formerly p53), known as the "guardian of the genome," is involved in the control of proliferation, differentiation, and apoptosis. TP53 mutations are considered a strong predictor
of poor survival and relapse in patients with chronic lymphocytic leukemia (CLL). The prognosis for patients with myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) with TP53 mutations is unfavorable. Response to treatment is usually short-lived, and the risk of relapse after allogeneic stem cell transplantation (allo-SCT) in this group of patients is increased."

Preparation and development of material (applies only to contractors)

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