BETA-2 MICROGLOBULIN
Material: Blood
Test price: PLN 50
Waiting time for the result: the result will be available no later than the next business day
Reservation:
Test price: PLN 50
Waiting time for the result: the result will be available no later than the next business day
Reservation:
- Check the opening hours of the collection point and where an appointment is required.
Preparation for the examination
General
- The material for testing is blood.
- The patient does not need to fast. It is recommended to drink a glass of water approximately 30 minutes before the examination.
Description
It is a protein that is a subunit of the human histocompatibility complex (HLA), present in the cytoplasmic membranes of all nucleated cells. Under physiological conditions, it undergoes filtration in the renal glomeruli and reabsorption in the proximal tubule. Elevated serum levels of B2 microglobulin in the presence of normal glomerular filtration suggest increased production or release of this protein.
Increased B2 microglobulin secretion is observed in a number of conditions, including Wilson's disease, Fanconis syndrome, nephrocalcinosis, cystinosis, chronic potassium deficiency, interstitial nephritis, connective tissue diseases such as rheumatic arthritis and Sjogren's syndrome, upper urinary tract infections, toxic kidney diseases, and exposure to heavy metals such as cadmium and mercury. Elevated levels may accompany lymphoproliferative disorders such as multiple myeloma, chronic B-cell leukemia, Hodgkin's disease, systemic lupus erythematosus, Crohn's disease, and certain viral infections. Measurement of B2 microglobulin is considered a sensitive method for diagnosing proximal renal tubular dysfunction.
Increased B2 microglobulin secretion is observed in a number of conditions, including Wilson's disease, Fanconis syndrome, nephrocalcinosis, cystinosis, chronic potassium deficiency, interstitial nephritis, connective tissue diseases such as rheumatic arthritis and Sjogren's syndrome, upper urinary tract infections, toxic kidney diseases, and exposure to heavy metals such as cadmium and mercury. Elevated levels may accompany lymphoproliferative disorders such as multiple myeloma, chronic B-cell leukemia, Hodgkin's disease, systemic lupus erythematosus, Crohn's disease, and certain viral infections. Measurement of B2 microglobulin is considered a sensitive method for diagnosing proximal renal tubular dysfunction.
Preparation and development of material (applies only to contractors)
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