BETA-2 MICROGLOBULIN
Material: Blood
Price of the study: 50 PLN
Waiting time for the result: result no later than the next working day
Booking:
Price of the study: 50 PLN
Waiting time for the result: result no later than the next working day
Booking:
- We perform the test without prior reservation. Check the working hours of the collection center
Preparation for the study
General
- The test material is blood.
- The patient does not need to be fasting.About 30 minutes before the test, it is advisable to drink a glass of water or bitter(unsweetened) tea.
Description
It is a protein that is part of the subunit of the tissue compatibility complex (HLA), and is present in the cytoplasmic membranes of all tubular cells. Under physiological conditions, it undergoes permeation in the glomeruli and reflux resorption in the proximal tubule. Elevated serum levels of B2 microglobulin with normal glomerular filtration suggest an increase in the production or release of this protein.
Increased secretion of B2 microglobulin is observed in a number of conditions, including Wilson's disease, Fanconis syndrome, renal calciphylaxis, cystinosis, chronic potassium depletion, interstitial nephritis, connective tissue diseases such as gouty arthritis and Sjogren's syndrome, upper urinary tract infections, toxic kidney disease, and exposure to heavy metals such as cadmium and mercury. Increased levels can accompany lymphoproliferative diseases such as multiple myeloma, chronic B-cell leukemia, Hodkin's disease, generalized visceral lupus, Crohn's disease, and certain viral infections. Measurement of B2 microglobulin is considered a sensitive method in the diagnosis of proximal tubular renal dysfunction.
Increased secretion of B2 microglobulin is observed in a number of conditions, including Wilson's disease, Fanconis syndrome, renal calciphylaxis, cystinosis, chronic potassium depletion, interstitial nephritis, connective tissue diseases such as gouty arthritis and Sjogren's syndrome, upper urinary tract infections, toxic kidney disease, and exposure to heavy metals such as cadmium and mercury. Increased levels can accompany lymphoproliferative diseases such as multiple myeloma, chronic B-cell leukemia, Hodkin's disease, generalized visceral lupus, Crohn's disease, and certain viral infections. Measurement of B2 microglobulin is considered a sensitive method in the diagnosis of proximal tubular renal dysfunction.
Development and preparation of material (applies to contractors only)
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