Chromogranin A

• The material for testing is blood.
• Approximately two weeks before the test, it is recommended to discontinue proton pump inhibitors
  and prazoles, which can cause falsely elevated results.
  Any discontinuation of medication should be discussed with your doctor beforehand!
• The patient must fast for at least 12 hours after consuming the last meal, unless the doctor recommends otherwise (e.g. performing the test after a meal)

• For children up to 3 years of age, it is recommended to collect blood half to one hour after feeding.

• For children up to 3 years of age, it is recommended to collect blood half to one hour after feeding.

Please report for testing in the morning (7:00-9:00 AM).
Samples brought from outside will not be accepted for testing.

Chromogranin A is a protein (glycoprotein) considered a tumor marker. It is produced in the cells of endocrine tumors of the gastrointestinal tract. Chromogranin A concentration, along with other tests, is used to determine the endocrine nature (carcinoid, pheochromocytoma) of tumors located in the stomach, intestines, or pancreas.
The test is ordered in the case of:
• Pheochromocytoma is suspected as a cause of secondary hypertension; this is evidenced by sudden, large increases in blood pressure, combined with pale skin and a rapid heart rate. This is a benign tumor usually located in the adrenal medulla.
• Suspected neuroendocrine tumor of the gastrointestinal tract; abdominal pain, constipation, diarrhea indicate such a diagnosis.
• Monitoring the treatment of neuroendocrine tumors.

Symptoms that may be caused by neuroendocrine tumors include:
• increased heart rate,
• high blood pressure,
• sudden redness of the face and neck,
• nausea,
• vomiting and diarrhea,
• coughing and wheezing.

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