Chromogranin A

• The test material is blood.
• About 2 weeks before the test it is recommended to stop taking drugs from the group of proton pump inhibitors
  proton pump inhibitors, as well as drugs from the group of prazole, which can cause a false overestimation of the results.
  Discontinuation of drugs absolutely must be consulted in advance with the attending physician!!!
• The patient must be fasting, at least 12 hours after eating the last meal, unless otherwise instructed by the doctor (e.g., performing the test after a meal)

• For children under 3 years of age, it is recommended to draw blood from half to one hour after feeding.

• For children under 3 years of age, it is recommended to draw blood from half to one hour after feeding.

You should report for the test in the morning ( 7:00-9:00).
Samples brought from outside are not accepted for testing.

Chromogranin A is a protein (glycoprotein), considered one of the tumor markers. It is produced in the cells of endocrine tumors of the gastrointestinal tract.Determination of chromogranin concentration, along with other tests, is used to determine the endocrine(carcinoma, pheochromocytoma)nature of the tumor located in the stomach, intestines, pancreas.
The test is ordered in the case of:
- Suspicion of pheochromocytoma as a cause of secondary hypertension; this is evidenced by sudden, large increases in blood pressure values, combined with pallor of the skin and accelerated heart rate. It is a benign neoplasm usually localized in the adrenal medulla.
- Suspected neuroendocrine tumor of the gastrointestinal tract; this diagnosis is indicated by abdominal pain, constipation, diarrhea.
- Monitor the treatment of neuroendocrine tumors.

Symptoms that can be caused by neuroendocrine tumors are:
- accelerated heart rate,
- high blood pressure,
- sudden flushing of the face and neck,
- nausea,
- vomiting and diarrhea,
- coughing and wheezing.

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