Coagulation factor II

• The material for testing is blood.
• The patient must not be undergoing treatment with high molecular weight heparin.
• The patient does not need to fast.

Samples brought from outside are not accepted for testing.

Coagulation factor II (prothrombin) is a protein produced in the liver with the help of vitamin K. It is a precursor to thrombin, a key enzyme involved in coagulation. This test is performed to diagnose coagulation disorders. Factor II deficiency can be caused by severe liver disease, vitamin K deficiency, or autoantibodies. Symptoms of prothrombin deficiency include tendency to bruise, bleeding from mucous membranes, prolonged bleeding after procedures, and heavy menstrual bleeding. Elevated prothrombin activity can lead to venous thrombosis.

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