EBV (Epstein-Barr virus) EBNA IgG

• The test material is blood.
• The patient does not need to be fasting.About 30 minutes before the test it is advisable to drink a glass of water.

Epstein-Barr virus (EBV) is one of the most widespread human viruses of the type

Herpes. The virus is transmitted through saliva, the droplet route but also through blood transfusion

and organ transplantation. Epstein- Barr virus causes infectious mononucleosis (a disease of the

Pfeiffer's), a disease characterized by fever, pharyngitis and lymphadenopathy, often also

With enlargement of the liver and spleen, rarely with a rash. When the infection first occurs

in childhood, is usually asymptomatic.

The main goal of EBV diagnosis in people with healthy immune systems is to distinguish between

Between fresh and past infection. A variety of serological methods are used for this.

The immune system of a healthy person is able to quickly fight off reactivation of the virus.

However, in people with impaired immune systems (e.g., during immunosuppressive therapy

post organ transplant or HIV infected) EBV can spread in the

uncontrollably and cause severe lymphoproliferative disorders.

The immune response to EBV infection is characterized by the production of antibodies

Against EBV antigens: virus capsid antigens (VCA), antigens

nuclear antigen (EBNA) and early antigen (EA).

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