HLA-Cw6 (psoriasis)

Material: Blood
Test price: PLN 260
Waiting time for results: result after 12 working days
Reservation:

  • We only perform testing at selected collection points/hours – PLEASE NOTE! Check testing hours and where appointments are required.

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Preparation for the examination

General

  • The material for testing is blood.
  • The patient does not need to fast. It is recommended to drink a glass of water approximately 30 minutes before the examination.

Important

Samples brought from outside are not accepted for testing.

Description

HLA-Cw6 testing is performed to distinguish rheumatoid arthritis (RA) from psoriatic arthritis, ankylosing spondylitis (AS), and osteoarthritis, and to differentiate the different forms of psoriasis.
Psoriasis is the most common skin disease, affecting 5-10% of people worldwide, and approximately 2% in Poland. In addition to skin lesions, it can also manifest as a joint condition, which is extremely difficult to diagnose due to its nonspecific symptoms and similarity to other joint diseases.
The underlying cause of the disease is complex and not fully understood. It is known to be a hereditary condition, whose symptoms can be triggered by a variety of external factors, such as infections, medications, stress, hormonal imbalances, poor diet, and stimulants.
Psoriatic arthritis does not differ significantly from other joint diseases in terms of its manifestations. It usually begins with malaise, fever, pain, and joint swelling. There may be periods of improvement and exacerbation of symptoms. In 50–70% of patients, inflammation affects several small joints. In women, the disease may mimic rheumatoid arthritis. In men, symptoms are primarily concentrated in the hip and spine. Inflammation of ligaments and tendons, particularly the Achilles tendon, is common.
Skin symptoms: papules, pustules, eruptions with characteristic silvery scales, scaly, patchy lesions, inflammatory lesions affecting large areas of skin, "pitting" nails, pinpoint bleeding.
Joint symptoms: tendonitis, primarily Achilles, "sausage fingers," stiffness, pain, swelling, and tenderness around the joints, pain in one or more joints simultaneously, difficulty moving, nocturnal back pain, morning stiffness, and fatigue.
Other symptoms: eye inflammation, ascending aorta inflammation, increased indicators: ESR, CRP, IgA, negative rheumatoid factor and anti-CCP antibodies in the blood serum.
The test should be performed if:
• there is a family history of psoriasis
• there is joint pain of unknown etiology
• there is tendonitis
• there are recurrent skin symptoms

Preparation and development of material (applies only to contractors)

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