Osteocalcin

• The material for testing is blood.
• Approximately 30 minutes before the examination, it is recommended to drink 1 glass of water only.
• The patient must fast for at least 12 hours after consuming the last meal, unless the doctor recommends otherwise (e.g. performing the test after a meal)
• You should not drink coffee, flavored water, drinks such as cola light/cola “zero”, energy drinks, or juices.
• You should not eat meals, snacks, fruits, vegetables, breath fresheners, chew gum, or smoke cigarettes.

• For children up to 3 years of age, it is recommended to collect blood half to one hour after feeding.

• For children up to 3 years of age, it is recommended to collect blood half to one hour after feeding.

Samples brought from outside are not accepted for testing.

Osteocalcin is one of the major non-collagenous bone proteins, constituting 3% of the total bone protein.

Bone tissue undergoes dynamic processes of formation and resorption. Osteocalcin is believed to participate in bone formation, as it is produced by osteoblasts, the primary cells for bone formation. Osteocalcin is also directly influenced by calcium-regulating hormones (calcitonin, parathyroid hormone, vitamin D), which are essential for proper bone mineralization.

Increased osteocalcin levels can occur in a number of different diseases, including osteomalacia, Paget's disease, hyperthyroidism, primary hyperparathyroidism, and renal osteodystrophy. Osteocalcin levels may also increase in postmenopausal osteoporosis, which is associated with increased or decreased bone remodeling.

Decreased osteocalcin levels have been reported in cases of hypoparathyroidism and during long-term corticosteroid therapy.

Osteocalcin is useful in monitoring mineral and metabolic status and bone health.

Enter one-time code:Show
Invalid code entered. Please try again.