Panel Chronic inflammatory bowel disease
Test price: PLN 190.00
Waiting time for results: result after 7 working days
Reservation:
- Check the opening hours of the collection point and where an appointment is required.
Preparation for the examination
General
- The material for testing is blood.
- The patient does not need to fast. It is recommended to drink a glass of water approximately 30 minutes before the examination.
Description
The test detects antibodies:
against exocrine cells and pancreatic antigens (e.g. rPAg1=CUZD1 and rPAg2=GP2) for the diagnosis of Crohn's disease
against Saccharomyces cerevisiae in the diagnosis of Crohn's disease
anti-intestinal goblet cell antibody in the diagnosis of ulcerative colitis
anti-granulocyte cytoplasmic antibody (pANCA) in the diagnosis of ulcerative colitis
against DNA-bound lactoferrin in the diagnosis of ulcerative colitis.
Antibodies are detected using polyvalent IgAG antiserum - according to the latest reports, the use of such antiserum increases the detection of specific autoantibodies.
Crohn's disease is an autoimmune disease of the intestinal mucosa. The first symptoms of CD include fatigue, pain in the right hypogastric region, and (mostly bloody) diarrhea. These symptoms may be accompanied by fever of unknown cause, significant weight loss, nausea, and vomiting. CD can also progress gradually without diarrhea. About half of CD patients experience secondary intestinal symptoms, which in rare cases can appear months or years before the onset of characteristic intestinal symptoms. Secondary symptoms include joint pain and inflammation, skin disorders (e.g., erythema nodosum, pyoderma gangrenous, rosacea), and eye inflammation (e.g., uveitis). These symptoms usually resolve with treatment.
Ulcerative colitis (UC) begins in the rectum and gradually spreads upward through the gastrointestinal tract. The main clinical manifestations are recurrent diarrhea, intestinal bleeding, and colic. Clinical manifestations outside the gastrointestinal tract include sacroiliitis and ankylosing spondylitis, peripheral arthritis with inflammation extending to large joints, primary sclerosing cholangitis, erythema nodosum, uveitis (iris/iritis and ciliary body), episcleritis, osteoporosis, and osteopenia.
Preparation and development of material (applies only to contractors)
805
Crohn's disease, ulcerative colitis, anti-intestinal goblet cell antibodies, anti-pancreatic exocrine cell antibodies (rPAg1, rPAg2), anti-granulocyte autoantibodies (pANCA)
