P/cp neutrophil cytoplasmic antigen ANCA (pANCA and cANCA) method IIF
Material: Blood
Test price: PLN 70.00
Waiting time for results: result after 7 working days
Reservation:
Test price: PLN 70.00
Waiting time for results: result after 7 working days
Reservation:
- Check the opening hours of the collection point and where an appointment is required.
Preparation for the examination
General
- The material for testing is blood.
- The patient does not need to fast. It is recommended to drink a glass of water approximately 30 minutes before the examination.
Description
Anti-granulocyte antibody testing is used to diagnose vasculitis.
cANCA antibodies demonstrate high specificity and sensitivity for Wegener's granulomatosis.
This is a chronic
disease characterized by fever and granuloma formation, primarily affecting the nasopharynx, lungs
, and kidneys.
The titer of these antibodies correlates
with clinical disease activity.
Anti-myeloperoxidase antibodies, which are present as pANCA antibodies, may indicate life-threatening conditions
such as granulomatosis rapid progressiva, polyangiitis microscopica, and other forms of vasculitis.
pANCA is also detected in ulcerative colitis and cholangitis primaria scleroticans.
The test is performed using the indirect immunofluorescence method using a granulocyte smear,
as well as the ELISA method, which allows the analysis of antibodies directed against individual antigens – enzymes, contained in granulocyte granules – proteinase 3, lactoferrin, myeloperoxidase, elastase, cathepsin G, lysozyme.
cANCA antibodies demonstrate high specificity and sensitivity for Wegener's granulomatosis.
This is a chronic
disease characterized by fever and granuloma formation, primarily affecting the nasopharynx, lungs
, and kidneys.
The titer of these antibodies correlates
with clinical disease activity.
Anti-myeloperoxidase antibodies, which are present as pANCA antibodies, may indicate life-threatening conditions
such as granulomatosis rapid progressiva, polyangiitis microscopica, and other forms of vasculitis.
pANCA is also detected in ulcerative colitis and cholangitis primaria scleroticans.
The test is performed using the indirect immunofluorescence method using a granulocyte smear,
as well as the ELISA method, which allows the analysis of antibodies directed against individual antigens – enzymes, contained in granulocyte granules – proteinase 3, lactoferrin, myeloperoxidase, elastase, cathepsin G, lysozyme.
Preparation and development of material (applies only to contractors)
618
P body p.neutrophil cytopl.antigen ANCA, ANCA, pANCA, cANCA
