P/c. against ANCA neutrophil cytoplasmic antigens (pANCA and cANCA) met. IIF
Material: Blood
Price of the study: PLN 65.00
Waiting time: result after 7 working days
Booking:
Price of the study: PLN 65.00
Waiting time: result after 7 working days
Booking:
- We perform the test without prior reservation. Check the working hours of the collection center
Preparation for the study
General
- The test material is blood.
- The patient does not need to be fasting.About 30 minutes before the test, it is advisable to drink a glass of water or bitter(unsweetened) tea.
Description
Anti-granulocyte antibody testing is performed in the diagnosis of vasculitis.
cANCA antibodies show high specificity and sensitivity for Wegener's granulomatosis.
It is a chronic, progressive
with fever and granuloma formation affecting primarily the nasopharynx, lungs
and kidneys.
The titers of these antibodies are correlated
with the clinical activity of the disease.
Myeloperoxidase antibodies, which are present in the form of pANCA antibodies, can indicate life-threatening conditions
i.e. Gromerulonephritis rapid progressiva, Polyangiitis microscopica and other forms of vasculitis.
pANCA is also detected in the course of Colitis ulcerosa, Cholangitis primaria scleroticans.
The test is performed by indirect imunofluorescence using a smear of granulocytes,
as well as the ELISA method, which allows the analysis of antibodies directed against specific antigens - enzymes, contained in granulocyte granules - proteinase 3, lactoferrin, myeloperoxidase, elastase, cathepsin G, lysozyme.
cANCA antibodies show high specificity and sensitivity for Wegener's granulomatosis.
It is a chronic, progressive
with fever and granuloma formation affecting primarily the nasopharynx, lungs
and kidneys.
The titers of these antibodies are correlated
with the clinical activity of the disease.
Myeloperoxidase antibodies, which are present in the form of pANCA antibodies, can indicate life-threatening conditions
i.e. Gromerulonephritis rapid progressiva, Polyangiitis microscopica and other forms of vasculitis.
pANCA is also detected in the course of Colitis ulcerosa, Cholangitis primaria scleroticans.
The test is performed by indirect imunofluorescence using a smear of granulocytes,
as well as the ELISA method, which allows the analysis of antibodies directed against specific antigens - enzymes, contained in granulocyte granules - proteinase 3, lactoferrin, myeloperoxidase, elastase, cathepsin G, lysozyme.
Development and preparation of material (applies to contractors only)
618
Body p.antigens of neutrophil cytopl.ANCA, ANCA, pANCA, cANCA
