P/c. pemphigus (desmoglein 1 and desmoglein 3) and pemphigoid met. IIF
Material: Blood
Price of the study: 150 PLN
Waiting time: result after 25 working days
Booking:
Price of the study: 150 PLN
Waiting time: result after 25 working days
Booking:
- We perform the test without prior reservation. Check the working hours of the collection center
Preparation for the study
General
- The test material is blood.
- The patient does not need to be fasting.About 30 minutes before the test, it is advisable to drink a glass of water or bitter(unsweetened) tea.
Description
Antibodies to the desmosomes of the stratum spinosum and basement membrane of the epidermis are evaluated using indirect immunofluorescence.
These antibodies are found in autoimmune dermatoses characterized by the formation of blisters on the skin layers.
Pemphigus vulgaris is a severe disease of the skin and mucous membranes covered with squamous epithelium, progressing with deep acantholysis.
Often the first symptom is blisters in the mouth, occurring later also on the skin. As these blisters easily burst, painful erosions occur.
Untreated lesions spread to the entire skin. The presence of IgG class antibodies against desmosomes of the stratum spinosum confirms the diagnosis (prevalence 90%).
Antibody titers correlate with disease activity. These antibodies are also detected in a small number of cases of burns and drug rashes, but without clinical manifestation.
Pomphigoid bullosus is characterized mostly by itchy blisters on the skin and often inflamed skin without mucous membranes.
Patients are mostly people over the age of 70.
Pemphigus and Pemphigoid rarely occur together. Complications of these diseases include electrolyte disturbances and secondary infections.
These antibodies are found in autoimmune dermatoses characterized by the formation of blisters on the skin layers.
Pemphigus vulgaris is a severe disease of the skin and mucous membranes covered with squamous epithelium, progressing with deep acantholysis.
Often the first symptom is blisters in the mouth, occurring later also on the skin. As these blisters easily burst, painful erosions occur.
Untreated lesions spread to the entire skin. The presence of IgG class antibodies against desmosomes of the stratum spinosum confirms the diagnosis (prevalence 90%).
Antibody titers correlate with disease activity. These antibodies are also detected in a small number of cases of burns and drug rashes, but without clinical manifestation.
Pomphigoid bullosus is characterized mostly by itchy blisters on the skin and often inflamed skin without mucous membranes.
Patients are mostly people over the age of 70.
Pemphigus and Pemphigoid rarely occur together. Complications of these diseases include electrolyte disturbances and secondary infections.
Development and preparation of material (applies to contractors only)
609
Antibodies to pemphigus/pemphigoid, antibodies to desmosomes of the stratum spinosum of the epidermis,
