PROFILE 2- STD POLYCHECK

• The test material is blood.
• The patient does not need to be fasting.About 30 minutes before the test, it is advisable to drink a glass of water or bitter(unsweetened) tea.

The test quantitatively tests the concentration of 14 antibodies in the patient's serum, which are responsible for inflammation of various organs resulting from autoimmune diseases: SS-A 60, SS-B, Scl-70, PM/Scl-100, Sm, PCNA, dsDNA, ribosomal protein P0, CENP-B, AMA M2, PR3 (c-ANCA), MPO (p-ANCA), TPO, Tg.

The test can be performed in:
- people with a suspicion or diagnosis of one of the following diseases,
- people suffering from general complaints (muscle or joint pain, weight loss, lack of appetite, skin changes, kidney disorders, fatigue and weakness) or specific complaints from organs involved in autoimmune processes (eyes, liver, kidneys, lungs, skin and muscles, patients diagnosed with another autoimmune disease),
- people whose immediate family members have been diagnosed with an autoimmune disease,
- people who have come out weak-positive in previous years to check whether the disease is progressing,
- sick people to monitor treatment.

The test is useful in diagnosing:
a) systemic inflammatory connective tissue rheumatic diseases:
- polymyositis/myositis (PM/Scl-100)
- scleroderma (Scl-70, CENP-B, PM/Scl-100, AMA M2)
- mixed connective tissue disease (SS-A 60, SS-B)
- syndrome a (SS-A 60, SS-B, AMA M2)
- systemic lupus erythematosus (Sm, dsDNA, SS-A 60, SS-B, PCNA, ribosomal protein P0)
- CREST syndrome (CENP-B, Scl-70)
b) autoimmune systemic vasculitis:
- Wegener granulomatosis (PR3)
- microscopic arteritis (MPO, PR3)
- idiopathic crescentic glomerulonephritis (MPO)
- Churg-Strauss a syndrome
- nodular arteritis (PR3, MPO)
- autoimmune thyroid diseases (TPO, Tg)
- primary biliary cirrhosis (AMA M2, CENP-B)
- Goodpasture a syndrome (PR3)

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