Anti-endomysial and anti-gliadin IgA antibodies
Material: Blood
Test price: PLN 70.00
Waiting time for results: result after 7 working days
Reservation:
Test price: PLN 70.00
Waiting time for results: result after 7 working days
Reservation:
- Check the opening hours of the collection point and where an appointment is required.
Preparation for the examination
General
- The material for testing is blood.
- The patient does not need to fast. It is recommended to drink a glass of water approximately 30 minutes before the examination.
Important
Before the test, you should not eliminate foods containing gluten from your diet.
Description
This is a serological test that detects autoantibodies associated with celiac disease and several other gluten-related conditions.
These tests detect autoantibodies produced in the body in response to dietary proteins (gluten and gliadin) found in grains (wheat, rye, and barley).
These autoantibodies cause intestinal inflammation and lead to the destruction of the intestinal lining. This results in symptoms of malabsorption and malnutrition, such as diarrhea, weakness, weight loss, abdominal pain, bloating, exhaustion, oral ulcers, a tendency to bleed, bone and joint pain, and anemia. Adults may experience depression and a general feeling of illness, while children often experience anxiety and exhibit delayed growth and development.
Gliadin and endomysium (reticulin) antibody testing is performed to confirm the diagnosis of gluten-sensitive enteropathy (celiac disease in children, nontropical sprue in adults) and Duhring's dermatitis herpetiformis (a chronic blistering skin condition). It should also be performed on relatives of celiac disease patients to detect a predisposition to gluten-sensitive enteropathy. Furthermore, the assessment of these antibodies is helpful in monitoring the course of
the disease, supervising a gluten-free diet, and performing gluten tolerance tests.
IgA antibodies to gliadin and endomysium are virtually absent in healthy individuals and those with other intestinal conditions, and their prevalence among untreated individuals with gluten enteropathy is nearly 100%.
The following serological tests detecting specific autoantibodies are used to diagnose celiac disease:
Anti-tissue transglutaminase antibodies (anti-tTG) in the IgA class
Anti-endomysial antibodies (anti-EmA) in the IgA class
Anti-gliadin antibodies (AGA) in the IgG and IgA classes
These tests detect autoantibodies produced in the body in response to dietary proteins (gluten and gliadin) found in grains (wheat, rye, and barley).
These autoantibodies cause intestinal inflammation and lead to the destruction of the intestinal lining. This results in symptoms of malabsorption and malnutrition, such as diarrhea, weakness, weight loss, abdominal pain, bloating, exhaustion, oral ulcers, a tendency to bleed, bone and joint pain, and anemia. Adults may experience depression and a general feeling of illness, while children often experience anxiety and exhibit delayed growth and development.
Gliadin and endomysium (reticulin) antibody testing is performed to confirm the diagnosis of gluten-sensitive enteropathy (celiac disease in children, nontropical sprue in adults) and Duhring's dermatitis herpetiformis (a chronic blistering skin condition). It should also be performed on relatives of celiac disease patients to detect a predisposition to gluten-sensitive enteropathy. Furthermore, the assessment of these antibodies is helpful in monitoring the course of
the disease, supervising a gluten-free diet, and performing gluten tolerance tests.
IgA antibodies to gliadin and endomysium are virtually absent in healthy individuals and those with other intestinal conditions, and their prevalence among untreated individuals with gluten enteropathy is nearly 100%.
The following serological tests detecting specific autoantibodies are used to diagnose celiac disease:
Anti-tissue transglutaminase antibodies (anti-tTG) in the IgA class
Anti-endomysial antibodies (anti-EmA) in the IgA class
Anti-gliadin antibodies (AGA) in the IgG and IgA classes
Preparation and development of material (applies only to contractors)
624
Anti-endomysial and gliadin IgA antibodies, endomysium, gliadin, tissue transglutaminase, celiac disease, gluten intolerance, reticulin, gluten
