Antibodies to endomysium and gliadin IgA
Material: Blood
Price of the study: PLN 70.00
Waiting time: result after 7 working days
Booking:
Price of the study: PLN 70.00
Waiting time: result after 7 working days
Booking:
- Check, the hours of operation of the collection center and where booking an appointment is required.
Preparation for the study
General
- The test material is blood.
- The patient does not need to be fasting.About 30 minutes before the test, it is advisable to drink a glass of water or bitter(unsweetened) tea.
Important
Do not eliminate gluten-containing foods from your diet before the test.
Description
This is a serological test that detects autoantibodies associated with celiac disease (visceral disease) and several other gluten-related diseases.
These tests detect autoantibodies that are produced in the body in response to food proteins (gluten and gliadin) present in cereals (wheat, rye and barley).
The above autoantibodies cause intestinal inflammation and lead to the destruction of the intestinal mucosa. This results in symptoms of malabsorption and malnutrition, such as diarrhea, weakness, weight loss, abdominal pain, bloating, exhaustion, ulceration of the oral mucosa, a tendency to bleeding, bone and joint pain and anemia (anemia). Adults may be depressed and have a general sense of illness, while children are often restless and show delayed growth and development.
Determination of antibodies to gliadin and endomysium (reticulin) is performed to confirm the diagnosis of gluten enteropathy (in children- celiac disease, in adults- non-tropical Sprue) and Dermatitis herpetiformis Duhring (a chronic skin condition characterized by blister formation). It should also be performed among relatives of patients with celiac disease to detect predisposition to gluten enteropathy. Besides, the evaluation of these antibodies is helpful in the process of monitoring the course
of the disease, supervision of a gluten-free diet and gluten load test.
Antibodies to gliadin and endomysium of the IgA class are practically absent in healthy people and those suffering from other intestinal diseases, and their prevalence among untreated people with gluten enteropathy is nearly 100%.
To diagnose celiac disease, the following serological tests detecting specific autoantibodies are used:
"Anti-tissue transglutaminase (anti-tTG) antibodies in IgA class
"Anti-endomysial antibodies (anti-EmA) in IgA class
"Anti-gliadin antibodies (AGA) in IgG and IgA class.
These tests detect autoantibodies that are produced in the body in response to food proteins (gluten and gliadin) present in cereals (wheat, rye and barley).
The above autoantibodies cause intestinal inflammation and lead to the destruction of the intestinal mucosa. This results in symptoms of malabsorption and malnutrition, such as diarrhea, weakness, weight loss, abdominal pain, bloating, exhaustion, ulceration of the oral mucosa, a tendency to bleeding, bone and joint pain and anemia (anemia). Adults may be depressed and have a general sense of illness, while children are often restless and show delayed growth and development.
Determination of antibodies to gliadin and endomysium (reticulin) is performed to confirm the diagnosis of gluten enteropathy (in children- celiac disease, in adults- non-tropical Sprue) and Dermatitis herpetiformis Duhring (a chronic skin condition characterized by blister formation). It should also be performed among relatives of patients with celiac disease to detect predisposition to gluten enteropathy. Besides, the evaluation of these antibodies is helpful in the process of monitoring the course
of the disease, supervision of a gluten-free diet and gluten load test.
Antibodies to gliadin and endomysium of the IgA class are practically absent in healthy people and those suffering from other intestinal diseases, and their prevalence among untreated people with gluten enteropathy is nearly 100%.
To diagnose celiac disease, the following serological tests detecting specific autoantibodies are used:
"Anti-tissue transglutaminase (anti-tTG) antibodies in IgA class
"Anti-endomysial antibodies (anti-EmA) in IgA class
"Anti-gliadin antibodies (AGA) in IgG and IgA class.
Development and preparation of material (applies to contractors only)
624
Antibodies to endomysium and gliadin IgA, endomysium,gliadin,tissue transglutaminase,celiac disease,visceral disease,gluten intolerance,reticulin,gluten
