Anti-smooth muscle antibodies (ASMA)

Material: Blood
Test price: PLN 62.00
Waiting time for results: result after 7 working days
Reservation:

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Preparation for the examination

General

  • The material for testing is blood.
  • The patient does not need to fast. It is recommended to drink a glass of water approximately 30 minutes before the examination.

Description

Antibodies against smooth muscle may be present in serum in various liver diseases (chronic hepatitis, cirrhosis).
Determining these antibodies is particularly important in the diagnosis of autoimmune chronic active hepatitis (CAH).
They can also be detected in infectious mononucleosis and other viral diseases, as well as in lupus erythematosus, breast cancer, ovarian cancer, and malignant melanoma, but they do not play a significant diagnostic role. After viral hepatitis, antibody titers usually decline rapidly.

High concentrations of antismooth muscle antibodies indicate chronic active hepatitis (antibody prevalence is 70%).
IgG and IgM antibody titers may correlate with disease activity. CAH occurs primarily in women, and half of cases develop before the age of 30.

Low titers of anti-smooth muscle antibodies are found in patients with primary biliary cirrhosis (50%), alcoholic cirrhosis, biliary obstruction and in approximately 2% of asymptomatic individuals.

Preparation and development of material (applies only to contractors)

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