Calcium/creatinine ratio in a urine sample

• The material for testing is urine from the second micturition (portion of urine)
• The patient does not need to fast.
• The patient typically collects urine into a vacuum container, then tightens the cap and peels off the sticker. Under the sticker is a hole for the included collection tube. The patient then places the collection tube on the designated hole, and the tube automatically draws in the urine. The patient brings this collection tube for analysis, and the patient disposes of the large container containing excess urine.
  If the sample submitted is insufficient, the laboratory reserves the right to cancel the analysis.
• The tube containing the collected material must be signed.

• To perform the test on a young child, purchase a special bag from the pharmacy (one for boys and one for girls).
  Then, follow the instructions on the bag.
  Place the bag containing urine into a disposable urinalysis container
  and label the sample container (do not transfer urine from the bag to the container).
  The test is performed on the second portion of urine (the second void).

The Ca/creatinine ratio measures the amount of calcium in the tested urine, calculated as creatinine excreted. It is used to assess the degree of calcium excretion in the urine and to estimate the degree of hypercalciuria. Hypercalciuria is a condition characterized by increased calcium excretion in the urine or an elevated calcium-creatinine ratio. Chronic hypercalciuria can lead to urolithiasis and impaired renal excretory function.
Urinary calcium excretion (calciuria) depends on age, diet, and the degree of calcium absorption in the intestines.
Factors affecting calciuria:
• medications
• hyperparathyroidism
• long-term immobilization
• bone metastases
• idiopathic hypercalciuria – is diagnosed when hypercalciuria is found in a person on a diet with a standard amount of dairy products, with normal kidney function, without disturbances in the concentration of calcium, phosphorus and magnesium in the serum, without diagnosed tubular acidosis and endocrine diseases
• dietary factors
• excessive sodium intake
• increased consumption of animal protein
• excessive alcohol consumption
• increased consumption of simple sugars

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