HPA-1 diagnosis of platelet conflict in pregnant women

Material: Blood
Price of the study: 200 PLN
Waiting time: result after 35 working days

  • We perform the test without prior reservation only at selected intake points/hours - NOTE! Check the hours of the tests

Luxmed collection points

Preparation for the study


  • The test material is blood.
  • The patient does not need to be fasting.About 30 minutes before the test, it is advisable to drink a glass of water or bitter(unsweetened) tea.


The HPA-1a antigen phenotype test can be performed regardless of whether the patient is pregnant or not, and in justified cases it is advisable to perform the antigen determination even before the planned pregnancy, as well as, for example, in the father of the child in a situation where the patient turns out to be HPA-1a negative.
No referral from a doctor is needed to perform the test.
Patients should report for the test with an identity document and completed form of informed consent for the test (printable at www.luxmedlublin.pl,można or at the clinic). It is advisable for the patient to have her pregnancy card/book with her.


Platelet conflict is one of the maternal-fetal serological conflicts. It is analogous to the well-known RhD conflict, in which the RhD-negative woman produces antibodies to the RhD antigen of the fetus, but involves platelets, not erythrocytes.
The cause of platelet conflict is the production of antibodies by the mother against antigens on the platelets of the fetus or newborn. The production of antibodies occurs when the child of a woman who does not have the platelet antigen HPA-1a (HPA-1a negative) inherits such an antigen from the father. Fetal disease occurs without any symptoms in the mother and can occur as early as the first pregnancy.
Platelet conflict carries the risk of fetal thrombocytopenia (ITP) or neonatal thrombocytopenia (AIMPN). It occurs rarely ( 2% of the population), but is associated with serious complications. It can lead to intracranial hemorrhage, and this can even cause the death of the child; it can also set traces in the form of epilepsy or hemiparesis.
By performing the test, a woman is informed that she is HPA1a positive (98% of women) and is not at risk of conflict in the HPA1a antigen, or that she is HPA1a negative (2% of women) and should perform diagnostic tests during pregnancy and be under the care of gynecologists specializing in the treatment of platelet conflict.
The test is recommended for all pregnant women, especially those who had complications in their first pregnancy, had a miscarriage, lost a baby due to a stroke or the baby had symptoms of hemorrhagic diathesis.

Development and preparation of material (applies to contractors only)

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